Neuropharmacological effects of alfa-cypermethrin in rats
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چکیده
منابع مشابه
Neuropharmacological effects of alfa-cypermethrin in rats
Objective: To study the effect of α−cypermethrin (α−CP) on some neuropharmacological paradigms like motor coordination, pentobarbitone-induced sleeping time and pentylenetetrazole-induced (PTZ) convulsion as well as γ-aminobutyric acid (GABA) level in rat brain. Materials and Methods: Albino Wistar rats were the experimental animals. Different neuropharmacological paradigms like motor coordinat...
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Alfa-cypermethrin (α-CP) a synthetic pyrethroid (type-II) insecticide, dissolved in dimethyl sulfoxide (DMSO-1 mL) was given consecutive daily orally for 60 days at 1/10 LD50 (14.5 mg/kg). The animals were sacrificed on day 61. Biochemicals, cytochrome P450, b5 contents in liver along with antioxidant status, tissue residual concentration, and brain GABA level were studied. It increased the ser...
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ژورنال
عنوان ژورنال: Indian Journal of Pharmacology
سال: 2005
ISSN: 0253-7613
DOI: 10.4103/0253-7613.13849